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1. Natural compounds derived from plants could yield hundreds of new drugs
   NYBG scientist says the plant world has “great potential” as a source of new medicines There are probably at least 500 medically useful chemicals awaiting discovery in plant species whose chemical constituents have not yet been evaluated for their potential to cure or treat disease, according to a new analysis by a New York Botanical [...]
2. Nigeria: FG and Cost of Cancer Screening
   THE Federal Government’s recent directive to its hospitals to reduce the cost of cancer screening, though very commendable, is long overdue, considering that late diagnosis of the disease has resulted in the high rate of cancer related deaths in the country. Cancer is one of the leading causes of deaths in the world, especially in [...]
3. NMR Fine-Tuned for High-Content Metabolomics Screening
   Scientists report on the development of a nuclear magnetic resonance (NMR)-based method forscreening the metabolomic response of drug-treated mammalian cells to drug therapy. TheSanford-Burnham Medical Research Institute, and Rady Children’s Hospital investigators, say the highly sensitive, fast, and simple method is carried out in 96-well format, and could have particular utility as a method for high-throughput [...]
4. Ancient Chinese cures translate into modern Western medicines
   The Chem-TCM is the most comprehensive database of its kind and translates more than 12,000 chemicals from more than 300 Chinese herbs used in traditional Chinese medicine (TCM) into Western terminology. “Future researchers will now be able to better understand the chemical basis of remedies that have been in use for thousands of years,” says [...]
5. XXI Century Database of Traditional Chinese Medicine Released
   October 18, 2011 A comprehensive database developed by King’s College London researchers that features the chemical components found in traditional Chinese medicines has been released to market this month, allowing researchers to explore age-old remedies in the search for tomorrow’s new drugs. Provided under licence to Tim Tec LLC, a US-based life science supplier company, [...]
6. Body & Mind – HEALTH U.S. Doctor Cautious About HIV Vaccine
   A New York City-based infectious disease specialist said a new vaccine developed by Spanish scientists, which could turn HIV into minor infection status, is reason to be cautiously optimistic. Dr. Joseph Rahimian said Thursday news of an HIV vaccine is certainly exciting, but questions remain. “An HIV vaccine has been the holy grail for infectious [...]
7. Insulin May Help Treat Alzheimer’s
   Researchers are investigating insulin as a possible treatment for Alzheimer’s disease, and in a preliminary study, the results look promising.A study in the journal Archives of Neurology suggests that intranasal insulin – that is, delivered through the nose – may help with cognition and functioning in patients who have both mild and more severe dementia.It’s [...]
8. 7TH DUESSELDORF SYMPOSIUM ON IMMUNOTOXICOLOGY Biology of the Arylhydrocarbon Receptor
   Heinrich Heine University Duesseldorf September 21 – 24, 2011 AhR research has taken great momentum recently, with a number of seminal discoveries, especially regarding its role in physiological events. This has opened new arenas, attracted new groups into the field, and led to a steep interest in the potential of AhR as a therapeutic target [...]
9. Canadian-made virus shows promise as cancer treatment
   An Ottawa-based research team has developed a virus that is showing promise as a new way of attacking and shrinking cancer tumours while leaving healthy tissue alone. It’s early days in the still-experimental field of therapeutic cancer viruses, called oncolytic viruses. But this new study from researchers from the Ottawa Hospital Research Institute (OHRI) and the [...]
10. Genetic Link Predisposes to Mesothelioma
    An investigation led by scientists at the University of Hawaii Cancer Center, Honolulu, and Fox Chase Cancer Center, Philadelphia has identified germline mutations in the BAP1 gene that predispose individuals to malignant mesothelioma. The research, published online yesterday in Nature Genetics, describes two U.S. families with a high incidence of mesothelioma, as well as other [...]
11. Critical Protein Discovery Could Help Prevent Lethal Ebola Virus
    An international team of scientists has discovered a biochemical route used by the deadly Ebola virus to infect human cells.   Scientists say the discovery points the way to new drugs that could prevent or treat one of the world’s most lethal viral diseases. The Ebola hemorrhagic virus, which got its name from the central African [...]
12. Adding caffeine to sunscreen could guard against skin cancer
    Scientists have worked out how caffeine might protect against certain skin cancers – a finding that could lead to better sunscreens. The research, conducted in mice, suggests that caffeine changes the activity of a gene involved in the destruction of cells that have DNA damage and are therefore more likely to become cancerous. The scientists [...]
13. Five Genes May Be Tied to Lethal Prostate Cancer
    TUESDAY, Aug. 16 (HealthDay News) — In what may be a diagnostic advance, U.S. and Swedish researchers have linked five inherited genetic mutations to the development of a particularly aggressive and deadly form of prostate cancer. The findings could someday lead to development of an easy-to-administer blood test to screen for such mutations to help [...]
14. Suicide-Bombing Bacteria Could Fight Infections
    Like any good military unit, infectious bacteria have access to numerous weapons and efficient communication systems. But like soldiers in the field, they’re also susceptible to suicide bombers. Researchers have used the tools of synthetic biology to create an Escherichia coli cell that can infiltrate foreign bacteria and explode, killing off the pathogens along with [...]
15. MS genetic discovery casts doubt on vein theory
    Scientists have discovered 29 new genetic variations linked to multiple sclerosis, with many involving genes relevant to the immune system – a finding that they say bolsters the theory that MS is a primarily an autoimmune disease. The new study, published Wednesday in the journal Nature, is the largest-ever study on the genetics of multiple [...]
16. Genetic mutations cause schizophrenia
    More than 50 per cent of sporadic cases of schizophrenia are caused by new, or “de novo,” protein-altering mutations-genetic errors that are present in patients but not in their parents, a new research has shown. A group led by Maria Karayiorgou, MD, and Joseph A. Gogos, MD, PhD, examined the genomes of patients with schizophrenia [...]
17. Proteus Syndrom Gene Variant Identified
    Researchers have discovered the gene mutation that leads to Proteus syndrome, a condition that causes different parts of the body to grow faster and larger than others, HealthDay reports. With only about 500 cases known in the developed world, Proteus syndrome is rare. The condition is marked by a partial enlargement of the hands or [...]
18. Daily pill can prevent HIV infection
    The partners of people who have HIV can protect themselves from infection by taking a once-daily pill, two groundbreaking studies in Botswana, Kenya and Uganda have shown. The discovery could bring work to combat Aids close to a “tipping point”, experts say. Attempts to promote condom use to protect against HIV in the hardest-hit parts [...]
19. Scientists Discover Gonorrhea Resistant to Antibiotics
    (EndPlay Staff Reports) – A new untreatable strain of gonorrhea has been discovered in Japan and is causing concern in the United States. Scientists reported that the strain, which is named H041, is resistant to all known forms of antibiotics. The researchers discussed the findings at a Monday meeting in Canada about three days after [...]
20. A deadly new reason to avoid deer ticks
    Move over, Lyme disease: Another tick-borne illness is on the rise in various parts of the country, and this one can kill. Known as babesiosis, the disease is caused by a microscopic parasite that attacks blood cells, causing flu-like symptoms that can make it difficult to accurately diagnose. Like Lyme disease, which is caused by [...]