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BioScreening.net » ChemInformatics

1. Plexxikon Receives Key Patents on Novel Compounds for Multiple Programs
   BERKELEY, Calif.–(BUSINESS WIRE)–Plexxikon Inc. today announced the issuance of key composition-of-matter patents covering novel compounds discovered through the company’s Scaffold-Based Drug Discoveryâ„¢ platform. Plexxikon’s pipeline of preclinical and clinical stage product opportunities currently span potential treatments for cardio-renal disease, CNS disorders, inflammation, metabolic disease and oncology. Two of the three recently issued patents (U.S. patents [...]
2. Molecular Fingerprints Point The Way To Earlier Cancer Diagnosis And More Targeted Treatment
   ScienceDaily (Mar. 27, 2009) — Metabolites are molecular fingerprints of what your cells are up to and Dr. Arun Sreekumar wants to know the impression made by cancer. You’ve likely heard about metabolites; your physician probably screens for some known ones such as triglycerides or cholesterol at your annual physical. Scientists suspect we have about [...]
3. ZINC Database – emolecule repository
   What is ZINC? It is a free database of millions of commercially-available compounds for virtual screening in ready-to-dock format. Why is it needed? Compounds that are available today can become unavailable in six months because of unavailability of the underlying reagents. For most vendors, the list of available compounds is significantly smaller than the list [...]
4. Virtual Screening Gives Drug Design a Boost
   San Diego, CA (OBBeC) – Researchers at the University of California, San Diego, developed a unique computational approach to identify key compounds that could lead to new drugs to combat African sleeping sickness — a disease spread by the biting tsetse fly and caused by the parasite Trypanosoma brucei. Around 150,000 people per year get [...]
5. Otava develops virtual screening system
   Mathematical modelling in biology is often a problem with interactions estimation between a biomolecular target and small molecule compounds. Knowledge of this interaction allows the interruption of certain processes in cells, for example it can impede diseases such as cancer. This is why so many efforts focus on designing better models and algorithms for high-throughput [...]