ActiTarg Series · over 2,000 compounds
ActiTarg-P Protease Inhibitors
A screening set of molecules that contain chemical lattices present in compounds reported to possess various protease-inhibiting properties.
ActiTarg-P includes over 2,000 pre-filtered compounds from several chemical series. Structural constraints and novel pendants provide variability for hit optimization. A top diversity selection of 1,520 protease inhibitors is available in smaller sets of 3, 5, 10, 15, or 19 plates with 80 compounds per plate. Dense subsets listed on the legacy pages are ActiTarg-240, ActiTarg-400, ActiTarg-800, and ActiTarg-1,520. Compounds are available for cherry-picking and/or as the 1,520-compound collection in 96- or 384-well plates and in vials.
Lattices represented
| Protease context | Lattice type |
|---|---|
| Coagulation cascade | Various |
| Aspartyl | N-AcAla |
| MMP | Succinate-OH; acylGly-OH; sulfonylGly-OH; N-ArethylGly-OH; pyrimidine-trione |
Published screens
No peer-reviewed screens naming ActiTarg-P were located.
ActiTarg is one of TimTec’s targeted series. See the ActiTarg Series for the other letter collections.